Base-catalyzed cyclization of N-sulfonyl propargylamides to sulfonylmethyl-substituted oxazoles via sulfonyl migration.
نویسندگان
چکیده
The reaction of N-sulfonyl propargylamides in the presence of a base catalyst selectively affords 5-sulfonylmethyl oxazoles via 1,4-sulfonyl migration. Allenes have been established as the key intermediates. Experimental evidence has been provided to support a two-step mechanism in the cyclization.
منابع مشابه
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 78 10 شماره
صفحات -
تاریخ انتشار 2013